Gross won an Albert and Mary Lasker Foundation prize in 1974 for his discovery of what became known as the Gross mouse leukemia virus.
2.
The binding domain on the mouse leukemia virus is relatively generic, Kim said, so that the virus can bind to the receptors on most rodent cells.
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One of the most commonly used vectors, derived from mouse leukemia virus, can deliver genes into chromosomes, where, it is hoped, they will operate for a long time.
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Now that the influenza virus, HIV and a mouse leukemia virus have been found to use the same mechanism, it seems likely that many other viruses will be found to do so, too.
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First, the researchers will take cells called fibroblasts from the patients'skin and genetically engineer them to produce NGF by adding extra copies of the gene using a mouse leukemia virus modified to ensure that it shouldn't trigger cancer.
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To break through, most treatments have used a genetically modified virus _ usually the mouse leukemia virus _ as a carrier, or " vector, " for the DNA . Now, Vical and other companies are working to use nonviral vectors, which in the past have lacked the potency to deliver adequate amounts of genes to cells.
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